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Recovery depends on several things: how long the treatment lasted, the dose size, patient characteristics, and any pre-existing stomach movement issues [27]

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[27] on the antidiabetogenic effect of intestinal factors, and in 1929 by Zung & La Barre [28] on the release of a substance from intestinal mucosa with properties to decrease glycaemia, signalled the start of the development of the incretin concept and the study of the relationships between the gut and the endocrine pancreas