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In summary, GLP-1 receptor agonists exert anti-fibrotic effects in MASLD through the inhibition of hepatic stellate cell activation, the modulation of profibrotic signaling pathways, and the promotion of hepatocyte regeneration

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The American College of Cardiology recommends continuing baseline statin therapy in patients with established indications, as GLP-1 receptor agonists complement but do not replace proven lipid-lowering medications