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Research suggests that both have promise on their own: a large umbrella meta?analysis recently found that berberine supplementation significantly reduced fasting blood glucose (by about –0.77?mmol/L) and HbA1c (by –0.57?%) in people with metabolic disorders
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Common side effects like nausea, vomiting, diarrhea and appetite suppression can persuade folks to stop therapy altogether, and many GLP-1 benefits fade when treatment stops
