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In regard to mediating energy or glucose homeostasis, neurons of the myenteric plexus of the ENS are activated via duodenal glucose infusion 71 and by hormones released in response to nutrient sensing in the gut, such as GLP-1 from EECs and serotonin (5-HT) from enterochromaffin cells (ECs) 71,72,73,74
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Size:12.5 mg
Phase 2 trials showed 24.2% average weight loss at 48 weeks
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