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It should be noted that this gastric emptying effect tends to attenuate with chronic therapy, as documented in the MHRA Summary of Product Characteristics (SmPC)

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The ongoing 72-week STEP UP T2D trial will investigate semaglutide 7.2 mg in 512 adults with obesity and type 2 diabetes, with the primary objective to demonstrate superiority of semaglutide 7.2 mg against placebo on weight loss