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Clinical Profile of Exenatide To understand subsequent innovations, it’s helpful to summarize exenatide’s clinical profile (as the first GLP-1 RA): Efficacy: In trials, twice-daily exenatide (10 µg BID) typically reduced HbA₁c by approximately 0.8%–1.0% more than placebo by 30 weeks ( [61] ) ( [103] )
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10.1097/MD.0000000000034978 [DOI] [PMC free article] [PubMed] [Google Scholar] 44
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