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all displayed a single site for inhibition of Rox-Ex4 binding, and with IC 50 values consistent with the lower affinity site in GLP-1R expressing membranes where G α proteins were present (Figure 7A)
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The discussion examines which patients, particularly those with type 2 diabetes and cardiovascular risk, may benefit most, along with key limitations such as its exploratory design and gastrointestinal tolerability
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