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In Butsch et al., 2025's cohort of 461,382 adults, diagnosed muscle loss rose from 2.1% at 6 months to 3.0% at 12 months
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Led by researchers at University College London (UCL), it enrolled 200+ people with moderate PD and followed them for 96 weeks , measuring the progression of motor deficits with the MDS-UPDRS-3 as the primary endpoint
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