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Common warning signs include: Pain after eating that feels concentrated in the upper right abdomen or centre of the upper abdomen Pain spreading elsewhere , especially towards the back or shoulder blade area Nausea and vomiting that seem to come with pain rather than mild digestive upset Fever or feeling acutely unwell , which raises concern about inflammation or infection Jaundice or very pale stools , which can suggest a bile flow problem and needs prompt review Pain that is sharp, localised, and radiating is different from general treatment-related queasiness
