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3D whole-brain c-Fos imaging 24–26-week-old chow-fed hGLP1R mice (n = 15) and WT C57BL6/N littermates (n = 14) were single-housed and vehicle-dosed (SC + PO, 5 mL/kg) from 4 days before treatment start (day −4) to minimise the stressor effect associated with the drug dosing procedure