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Shortly after, a meta-analysis systematically searched the Chinese and English literature for eligible randomized controlled trials to compare glucose-lowering effects of metformin and acarbose, which also implied that the effect of metformin is at least as good as that of acarbose ( To the best of our knowledge, this study is the first of its kind to document the interaction of between pharmacotherapies and dietary intakes of macronutrients in patients with T2DM