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Sensory symptoms are often the earliest manifestations and may include: Tingling or 'pins and needles' sensations (paraesthesia), typically beginning in the feet or hands Numbness or reduced ability to feel temperature, pain, or touch Burning sensations or shooting pains, particularly in the extremities Increased sensitivity to touch (hyperaesthesia) or pain from normally non-painful stimuli (allodynia) Loss of balance or coordination due to reduced proprioception (awareness of limb position) Motor symptoms may develop if neuropathy affects motor nerves, including muscle weakness, difficulty with fine motor tasks (such as buttoning clothes), foot drop, or muscle cramps and twitching
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