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Phase 3 TRIUMPH-4 results (68 weeks): 9mg dose: 26.4% average weight loss (29.1 kg) 12mg dose: 28.7% average weight loss (32.3 kg) Placebo: 2.1% average weight loss The 12mg retatrutide group lost an average of 71.2 pounds
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Dose reduction may work for select patients, but complete discontinuation remains difficult without alternative therapies or a multidisciplinary approach
