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Updated NICE guidelines The recent update to the NICE (2015a) guideline on management of type 2 diabetes recommends dual first-line therapy with metformin and an SGLT2 inhibitor with proven CV benefit in people with type 2 diabetes who have chronic HF or established ASCVD (myocardial infarction, angina, ischaemic stroke/transient ischaemic attack or peripheral arterial disease)
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