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A novel DPP-4 inhibitor Gramcyclin A attenuates cognitive deficits in APP/PS1/tau triple transgenic mice via enhancing brain GLP-1-dependent glucose uptake
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Studies conducted in animal models reported the presence of GLP-1R mRNA in the glomerulus and the initial part of proximal convoluted tubes, with no mRNA expression in other sites of the nephron [16]
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