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Semaglutideโs Australian product information says energy intake during an unrestricted meal was lower with treatment, and liraglutide and tirzepatide product information both describe reduced food intake as part of the mechanism behind weight loss
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While gastrointestinal AEs such as nausea and vomiting dominate safety reports 8 and recent pharmacovigilance studies highlight increasingly recognized risks including acute pancreatitis, nephritis, hypotension, and syncope 9,10,11 , emerging data suggest that GLP-1 RAs may be associated with neurological adverse events (NAEs) 12,13