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how long have glp-1 drugs been around receptor agonists are increasingly used to treat type 2 diabetes and obesity, and trials shown reductions in cardiovascular risk and slowing of kidney failure. Adverse events are mostly gastrointestinal Reconciling GLP-1s and Pancreatitis
Reconciling GLP-1s and Pancreatitis
The GLP1R variant rs10305420 is a missense variant in the signal peptide region, and may influence stability of the peptide secondary structure (Extended Data Fig
Lancet 402 , 429–431 (2023)