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Clinical trials demonstrate that people who remain on GLP-1 therapy experience stable weight for years, whereas those who stop see rapid increases in food intake and body weight

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On a cellular level, this molecule counteracts the phosphorylation and the inactivation of inhibitor of kappa B alpha (IκBα), which is responsible for the sequestration of NF-κB in the cytoplasm, thus reducing the concentration of the pro-inflammatory cytokines that are primarily involved in the pathogenesis of lupus[30]