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These medications act directly on the brain’s appetite centers to reduce hunger and increase feelings of fullness

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Neurogastroenterol Motil (2004) 16(Suppl 2):3–16.10.1111/j.1743-3150.2004.00553.x 135 DuraffourdCDe VadderFGoncalvesDDelaereFPenhoatABrussetBet alMu-opioid receptors and dietary protein stimulate a gut-brain neural circuitry limiting food intake