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Pyridoxamine analogues scavenge lipid-derived gamma-ketoaldehydes and protect against H2O2-mediated cytotoxicity
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The HTN group had a −6.24 mmHg change for semaglutide and a −1.62 mmHg for placebo, while this was more pronounced for the HTN130 group (−12.07 mmHg for semaglutide and −7.02 mmHg for placebo) and greater yet again for the HTN140 group (−17.41 mmHg for semaglutide and −12.57 mmHg for placebo)