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Weight-loss injections such as GLP-1 agonists (including semaglutide and tirzepatide) are increasingly used — but they can affect how some oral medications are absorbed, including contraception and Hormone Replacement Therapy (HRT) New

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GLP-1 and exendin-4 show a similar nM affinity while glucagon, secretin, VIP and GLP-2 have at least a hundred times lower affinity for the GLP-1 receptor