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[DOI] [PMC free article] [PubMed] [Google Scholar] 171.Lin H.V., Wang J., Wang J., Li W., Wang X., Alston J.T

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They showed that administration of their modified long-acting OXM peptide led to a decrease in food intake and increased weight loss in addition to improved metabolic profile, superior to GLP-1 alone over 14 days in diet-induced obese (DIO) mice ( in vitro and led to body weight loss of 30% in DIO mice over 14 days compared to liraglutide treated mice ( db/db mice