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Several studies have reported cases of regurgitation, vomiting, and aspiration in patients using GLP-1 RAs despite adherence to the fasting guidelines established by the American Society of Anesthesiologists (ASA), which recommend fasting for clear liquids up to two hours before surgery, light meals up to six hours before, and fatty meals up to eight hours before anesthesia induction [42]

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[30], Trp-306 5.36 –Ala was expressed as a functional receptor in our system, albeit with 190-fold lower GLP-1 potency