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Further work in this area could integrate these GLP-1 responsive PBN neurons into currently known feeding circuits and behavioral circuits(Alhadeff et al., 2018), as started by work integrating the role of the arcuate nucleus input to the PBN(Campos et al., 2016)
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This oral formulation of GLP-1RA will be able to address the challenges of poor patient acceptance, adherence and persistence.[6,7,8] This oral semaglutide formulation will be a game-changer in the management of diabetes with its multiple benefits
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