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Retatrutide, a GIP, GLP-1 and glucagon receptor agonist, for people with type 2 diabetes: a randomised, double-blind, placebo and active-controlled, parallel-group, phase 2 trial conducted in the USA - The Lancet

Injected semaglutide binds to these GLP-1 receptors and reduces appetite for nearly a week, ultimately causing people to eat less and lose weight

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Common side effects of the drug include nausea, vomiting, diarrhea, constipation and indigestion