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Metabolic syndrome with elevated liver enzymes : Patients presenting with multiple metabolic risk factors (central obesity, hypertension, dyslipidemia, impaired fasting glucose) and persistently elevated ALT/AST may benefit from the comprehensive metabolic improvements offered by GLP-1 therapy
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50 , 51 , 52 , 53 , 54 In contrast, metabolic induction models in wild‐type C57BL/6 mice—typically fed a high‐fat diet—have illuminated the systemic contribution of insulin resistance and mitochondrial dysfunction to neuroinflammatory processes
