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A prominent abnormality is reduced SERCA2a expression and function, severely compromising SR calcium reuptake during diastole [58]
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大小:60粒膠囊
While proglucagon is expressed within the pancreatic alpha cells, the enteroendocrine L cells, and to a minor extent within the hypothalamus and brain stem, differential tissue expression of prohormone convertase 2 (PC2) and prohormone convertase 1/3 (PC1/3) allows for tissue-specific processing of proglucagon into either glucagon (via PC2) or glucagon-like peptide 1 (GLP-1) and glucagon-like peptide 2 (GLP-2) via PC1/3 [122]
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