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Castration-Resistant Prostate Cancer: From Uncovered Resistance Mechanisms to Current Treatments
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Thus, although much research is focused on defining the direct intrakidney effects of GLP-1 receptor agonists, it is possible that some of the benefits occur indirectly, as a result of GLP-1 receptor agonists’ ability to improve kidney risk factors, as well as via extrarenal systemic effects of these agents that are not yet fully defined, such as attenuation of low-grade systemic inflammation
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