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Semaglutide (Wegovy™) works by targeting one receptor to help control appetite and blood sugar, while Tirzepatide (Mounjaro™) targets two receptors, which can lead to potentially greater weight loss results in some patients

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In a recent phase 2 randomized trial, 9 weeks of low-dose semaglutide in 48 outpatient participants with alcohol use disorder led to reductions in some but not all measures of alcohol use and craving