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27 Importantly, GLP-1 action is short-lived, with a half-life of just 1–2 minutes in the bloodstream under normal physiological conditions, after which it is broken down by the enzyme dipeptidyl peptidase IV (DPP-4), resulting in a loss of its biological activity
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Most medical sources suggest that taking your dose up to two to three days early is safe, though one day is the typical recommendation
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