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Concurrently, high glucose suppressed the tumor suppressor TIF1γ, further amplifying Smad-mediated transcription and elevating the expression of pro-oncogenic genes, including the epithelial–mesenchymal transition markers N-cadherin and vimentin, thereby collectively fostering CRC progression
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2022 Canadian cardiovascular society guideline for Use of GLP-1 receptor agonists and SGLT2 inhibitors for cardiorenal risk reduction in adults
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