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Two Antidiabetic Drug Classes May Curb Alzheimer's Risk

Antagonism of rat beta-cell voltage-dependent K+ currents by exendin 4 requires dual activation of the cAMP/protein kinase A and phosphatidylinositol 3-kinase signaling pathways

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Third, transgenic mice with deletion of the GIP receptor (GIPR) were protected from weight gain on a high fat diet, leading to the inference that GIP signaling promotes obesity 29