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Frontiers | GLP-1R in diabetes mellitus: from basic discovery to therapeutics development

Short-acting RAs, such as exenatide (Byetta), lixisenatide and beinaglutide, have a duration of action of only a few hours after being subcutaneously injected., thus need multiple times injection daily

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Current evidence with GBTs does not consistently indicate excess loss of muscle mass or strength that would require additional management steps [164]