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From January 2024–June 2025, AOM tirzepatide initiations rose steadily (+239% cumulative increase, ~+0.01 points/month)
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Acting as incretin mimetics, they enhance glucose-dependent insulin secretion, suppress glucagon release, delay gastric emptying, and promote satiety, addressing several core abnormalities in T2DM pathophysiology (Ahmann et al., 2015)
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