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During this transition, intensive dietary support, increased physical activity, and sometimes behavioral therapy help anchor lifestyle changes so they persist when medication is reduced

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For semaglutide, that could mean starting at 0 } ‍ Potential Benefits of Microdosing GLP-1 Clinical trials have not specifically evaluated GLP-1 microdosing at sub-standard doses, and off-label lower-dose approaches have not been validated in randomized controlled trials