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Mientras que el componente GLP-1 reduce la ingesta calórica mediante la modulación del vaciado gástrico y la señalización de saciedad central, y el componente GIP potencia la sensibilidad a la insulina y favorece el almacenamiento lipídico subcutáneo seguro frente al visceral, el componente de glucagón actúa como un interruptor catabólico controlado
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