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Do biologics and GLP-1 work together for arthritis pain?

This bidirectional relationship between psychotropic medications and metabolic dysfunction creates a self-reinforcing pathogenic cycle: psychotropic medications worsen insulin resistance, which contributes to reduced treatment efficacy, often leading to dose escalation or polypharmacy

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Mitochondrial dysfunction arises from the combined effects of environmental and genetic factors and is closely linked to the onset of PD [60]