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Data presented are for the efficacy estimand unless otherwise noted CVD cardiovascular disease, HbA1c glycated hemoglobin, MACE major adverse cardiac events, MMO morbidity mortality obesity, T2D type 2 diabetes a MACE-5 comprised all-cause death, nonfatal myocardial infarction, nonfatal stroke, unstable angina requiring hospitalization or revascularization, and coronary revascularization Table 3

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